Telpride 80mg (Telmisartan)

Telpride 80mg (Telmisartan)

Product Details:


Telpride 80mg (Telmisartan) Price And Quantity

  • INR/Box
  • 10 Box

Product Description

Product Composition    :Telmisartan 80 mg

Brand Name                 :Telpride 80mg

Composition                 :Eachtablet Contain Telmisartan 80mg

Packing                        :10*10




1.     Pharmacodynamics:  Antagonizes the effect ofangiotensin II (vasoconstriction and aldosterone secretion) by blocking the

                                               angiotensinII (AT 1 receptor) in vascular smooth muscle and the adrenal gland, producingdecreased BP.

2.     Pharmacokinetics: 

a.)   Absorption:   T max is 0.5 to 1 h. Foodslightly reduces bioavailability of telmisartan, with an AUC reduction ofapproximately 6% with a 40 mg dose and 20% with a 160 mg dose. At 40 and 160mg, the bioavailability was 42% and 58%, respectively. Trough plasma concentrationswith daily dosing are approximately 10% to 25% of C max.

b.)   Distribution:  -Telmisartan is more than99.5% protein bound. Vd is approximately 500 L.

c.)   Metabolism:  -Telmisartan is metabolized byconjugation to form a pharmacologically inactive acyl glucuronide. Theglucuronide of the parent compound is the only metabolite that has beenidentified in human plasma and urine.

d.)   Elimination:  -Telmisartan half-life isapproximately 24 h and total plasma Cl is more than 800 mL/min. After IV or oraladministration, more than 97% is eliminated unchanged in feces via biliaryexcretion.



Treatment of hypertension; for the reduction of the risk ofMI, stroke, or death from CV causes in patients 55 y and older who are at highrisk of developing major CV events and are unable to take ACE inhibitors.


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